In addition, IHC staining with CDK4 and TSC1 antibodies revealed a negative correlation between CDK4 and TSC1 expression in the ccRCC tissue microarray (Spearman r = –0.3302, P = 0.0429, n = 38) (Fig. 1l). The gene discussed is TSC1; the disease is nonpapillary renal cell carcinoma.