The experimental group injected with pX330-sg-SNRPD2 of mice with MYC; p53-/- HCC showed a dramatic decrease in luciferase expression at day 33 after plasmid injection compared to that in control mice (injected with pX330-sg-NonTarget) (Fig. 2l). This evidence concerns the gene SNRPD2 and hepatocellular carcinoma.