Consistent with this, the JML-1 Ab blocked attachment of Siglec-6+ primary B-CLL cells to sTn+ CLL-BMSCs in an in vitro co-culture assay (2.35-fold decrease) (Fig. 4a), indicating the need for Siglec-6 in attachment of B-CLL cells to CLL-BMSCs. The gene discussed is EEF1A2; the disease is B-cell chronic lymphocytic leukemia.