Next, to determine if sTn expressed on CLL-BMSCs is the ligand that is mediating binding to Siglec-6, we performed immunoprecipitation with Siglec-6 Fc fusion protein on CLL and normal donor BMSCs followed by immunoblotting with sTn antibody. The gene discussed is EEF1A2; the disease is B-cell chronic lymphocytic leukemia.