CDK4 and neuroblastoma: We found diverse CDK regulation across cell lines: SK-N-BE(2)-C and SK-N-AS with miR-29 showed minimal changes, except for CDK2 downregulation in miR-29c-overexpressing SK-N-BE(2)-C; CHLA-255 displayed CDK4 and CDK6 downregulation, while SK-N-SH with miR-29b and miR-29c exhibited CDK4 and CDK2 downregulation, indicating unique regulatory profiles in NB cell lines (Supplementary Fig. S7E).