TPTE and melanoma: Of these, New York squamous cell carcinoma of the esophagus 1 (NY-ESO-1), melanoma-associated antigen A3 (MAGE-A3), and transmembrane phosphatase with tensin homology (TPTE) are so-called cancer germline antigens that are not expressed at all in healthy skin tissue and aberrantly activated in melanoma cells [11, 12].