MAPT and Alzheimer disease: This, and the fact that the MAPT locus risk variants previously reported in PD, AD, PSP, and CBD26,39,40,42 all resulted genome-wide significant in our dataset (and in complete and perfect LD with each other), supports the notion that the MAPT locus may be a common denominator at the crossroad of multiple etiologically close conditions such as FTD, AD,26 PSP, CBD,50 and PD.52