In relation to this latter point, it is worth noting that, per study design, we excluded all samples diagnosed with the logopenic variant in the current work (thus reducing potential diagnosis bias), and we verified that many of the historical AD risk loci (e.g., CR1, BIN1, CLU) reached negligible p values in our cohort, while the MOBP locus hit reported for FTD in the current work shows negligible p values in two recent AD GWASs. This evidence concerns the gene BIN1 and Alzheimer disease.