The current study also lays the foundations for future work aimed at further characterizing population-specific features of potential FTD-discriminant APOE haplotype(s) and the functional involvement and contribution of the MAPT H1c haplotype and RPSA-MOBP loci to pathogenesis in brain cortex of sporadic forms of FTD. The gene discussed is MAPT; the disease is frontotemporal dementia.