SP1 and intervertebral disk degenerative disorder: Thanks to multiple data integration via Genopyc we highlight the involvement of variants associated downstream to pathways that may be relevant to the IDD, such as SP1 (Xu et al. 2016), HIF1-α (Meng et al. 2018) and AP-2α (Li et al. 2020), that according to the literature are tightly associated with IDD.