The behaviour of HSA, such as the expression of cell markers, pathological features and molecular and functional subtypes, varies with the arising site (primary location) (Gorden et al., 2014; Kim et al., 2015; Lamerato‐Kozicki et al., 2006; Tomasetti & Vogelstein, 2015), and various tumour‐related factors probably affected biological behaviour. This evidence concerns the gene ALB and neoplasm.