Indeed, only 2 of the 8 patients with SLE who tested positive for anti-1833 Abs were also positive for Abs against human DNASE1 (r = 0.333, P = 0.226), and 2 different patients tested positive for anti-DNASE1L3 Abs (r = –0.059, P = 0.8345) (Figure 9, G and H, respectively), further demonstrating that these are not the same autoantibodies. Here, DNASE1L3 is linked to systemic lupus erythematosus.