NLRP12 and systemic lupus erythematosus: Unlike the C57BL6/N mice from Taconic Biosciences, the C57BL/6J mice from The Jackson Laboratory are known to harbor a point mutation in Nlrp12 that reduces neutrophil recruitment during inflammation (40), providing a mechanistic understanding of the increased mortality observed in Taconic Biosciences mouse models of pristane-induced lupus, although both strains were be rescued from mortality by LBme.