KMT2A and parathyroid gland disorder: To examine whether cyclin D2 upregulation involves transcriptional increases mediated by KMT2A, GATA3 and STAT3, we carried out siRNA knockdown experiments in HEK293T cells, which have been used by other researchers for experiments in cellular biology, molecular biology and biochemistry related to parathyroid disease studies.50, 51, 52