To further verify that STING pathway activation plays a determinant role in the tumor suppression resulted from the photothermally engineered bacteria therapy combined with CD47 nanobody, we cotreated the Colon26 tumor bearing mice with a STING pathway inhibitor H151 on the basis of bacteria‐mediated PTT combined with CD47 nanobody (Figure S33, Supporting Information). The gene discussed is CD47; the disease is neoplasm.