Therefore, TLR4 is widely involved in a variety of neurological diseases, such as cerebral infarction,23 cerebral hemorrhage,24 neurodegeneration,25 and mood disorders, including depression,26 and TLR4‐deficient mice exhibit improvements in neurological and/or behavioral outcomes in various cerebral infarction models.27 The gene discussed is TLR4; the disease is cerebral infarction.