Indeed, Rab11a‐exosome‐enriched sEVs secreted from Torin1‐treated Caco‐2 cells produced mild growth‐promoting effects on Caco‐2 cells cultured in low serum and these effects were selectively inhibited following incubation with an anti‐AREG antibody (Figure 2f,g), suggesting that AREG associated with stress‐induced Rab11a‐exosomes from multiple CRC cell lines can promote growth. This evidence concerns the gene AREG and colorectal carcinoma.