PLK1 and colorectal carcinoma: Compared to PLK1 wild‐type CRCs, the CRC cohort showed higher TMB (p < 0.001, Figure 2B) whereas similar TMB levels were observed in CRCs with PLK1 truncating and non‐truncating mutations (p = 0.34), suggesting that more genetic abnormalities were accumulated in PLK1‐mutated CRCs without obvious differences between truncating and non‐truncating mutations.