DYSF and neuromuscular disease caused by qualitative or quantitative defects of dysferlin: Dysferlin deficiency leads to the development of several rare progressive muscular dystrophies such as limb girdle muscular dystrophy 2B/2R (LGMD2B/2R) and Miyoshi myopathy (MM), collectively known as dysferlinopathies.[1, 2] In humans, dysferlinopathies have late‐teen onset in select proximal or distal limb‐girdle muscles, followed by progressive muscle weakness[3, 4] and significant muscle replacement by fat,[5, 6, 7] eventually resulting in permanent loss of ambulation.