Furthermore, SLC7A11 (P < 0.001), GPX4 (P < 0.001), and Nrf2 (P < 0.001) protein levels were significantly downregulated and TFRC protein level was (P < 0.001) upregulated in keloid tissues (Figs. 1F–1J). The gene discussed is SLC7A11; the disease is keloid.