TNF and atherosclerosis: GO analysis revealed that many DEGs were enriched mainly in the pathways of IL‐10 production and T‐cell differentiation (Table S4), and KEGG analysis revealed that the activities of several inflammatory signaling pathways, such as the TNF, IL‐17, lipid metabolism and atherosclerosis processes, the Janus kinase/signal transduction and activator of transcription (JAK/STAT), mitogen‐activated protein kinases (MAPK), nuclear factor‐kappa B and toll‐like receptor pathways, were downregulated (Figure 2F and Table S5).