In addition, the OR (95%CI) of stroke per SD increase in genetically predicted immune cells was 0.970 (0.952, 0.989) for CD40 on CD14+ CD16+ monocyte, 0.976 (0.962, 0.990) for CD40 on monocyte and 0.969 (0.948, 0.990) for CD40 on CD14+ CD16- monocyte. This evidence concerns the gene CD40 and stroke disorder.