In contrast, gene-predicted TLR1 was linked to arthrosis and chalazion, gene-predicted SNUPN was linked to pneumonia, gene-predicted KDELC2 was linked to uterine leiomyoma, and gene-predicted GCDH was linked to non-insulin-dependent diabetes mellitus without complications, all of which were considered detrimental. The gene discussed is TLR1; the disease is diabetes mellitus.