The PFS and OS results showed similar findings that both mean PFS (4.61 months, 95% CI: 2.60–6.62) and OS (17.56 months, 95% CI: 15.09–20.02) for NPC patients with PD-L1 ≥ 1% were longer than those for patients with PD-L1 < 1% (PFS: 3.39 months, 95%CI: 2.36–4.42; OS: 13.5 months, 95% CI: 6.65–20.35), but there was no significant subgroup difference (Figures 5, 6). Here, CD274 is linked to nasopharyngeal carcinoma.