Considering H. pylori inducing hnRNPA2B1 expression in GC, we investigated whether H. pylori infection could mediate hnRNPA2B1 to modulate tumor metabolism by assessing the alterations in glucose uptake, the production of pyruvate and lactate, and NADP+/NADPH ratios. The gene discussed is HNRNPA2B1; the disease is gastric cancer.