H. pylori as one of the most prevalent bacteria constructs a predominant risk factor, contributing to gastric mucosal inflammation and cancer transformation[14] It is known that H. pylori can activate various signaling pathways including NF‐κB and accelerate uncontrolled GC cell growth and metastasis.[15, 16] However, whether H. pylori mediates hnRNPA2B1 to lead to GC remains elusive. The gene discussed is HNRNPA2B1; the disease is cancer.