However, irrespective of whether expression of GABAA or GABAB receptor subunits were altered in colon cancer, expression of particular receptor subtypes (GABRA1, GABRA5, GABRD, GABRE, GABRG1, GABRG3, GABBR1, and GABBR2) was significantly associated with poor clinical outcome (Table 1). The gene discussed is GABBR1; the disease is colonic neoplasm.