However, the role of miR-132 is complex with other studies showing that miR-132 reduces β-amyloid accumulation and drives neurogenesis in the hippocampus.39,40 Thus, it is possible that the upregulation of Mir132 gene expression in the brains of hypertensive mice after stroke may be a compensatory response in order to promote repair of the injured tissue. Here, MIR132 is linked to stroke disorder.