Several key genes regulating metabolism (including ASNS, SLC1A3, DSC3, ATP6V1C2), transcriptional events and oncogenic signaling (PRKAA2 (also known as AMPK), ANXA10, GNG2, and CSAG1)) were significantly downregulated by ASNS deletion in the female CRC (Fig. 3B). The gene discussed is GNG2; the disease is colorectal carcinoma.