Especially interesting finding was that the DUSP6 knockdown cells displayed a gene expression pattern linked to dormant cancer cells such as inhibition of MYC, E2F1 targets, and the PI3K/AKT/mTOR signaling, as well as activation of the interferon response (Chang et al, 2022; Dhimolea et al, 2021; Kurppa et al, 2020; Marine et al, 2020). Here, E2F1 is linked to cancer.