Further, when the 1082 breast invasive carcinoma samples from the TCGA BRCA-dataset (Dataref: Cerami et al, 2012; de Bruijn et al, 2023; Gao et al, 2013) were divided to DUSP6high and DUSP6low groups based on their DUSP6 mRNA expression levels, HER2+ and luminal A subtypes were clearly enriched among the DUSP6high samples (Fig. 2E). The gene discussed is DUSP6; the disease is invasive breast carcinoma.