DUSP1 and cancer: The best characterized DUSP6 inhibitor molecule BCI ((E)-2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one), is a semi-allosteric inhibitor of both DUSP1 and 6 that phenocopies genetic DUSP6 inhibition in several cancer models (Kong et al, 2023; Korotchenko et al, 2014; Molina et al, 2009; Vainonen et al, 2021).