SPP1 and human papilloma virus infection: Among them, SPP1 was associated with tissue homeostasis, anatomical structure homeostasis, regulation of lipid transport and localisation, lipid export from cell (Fig. 9A), and also involved in ECM (Fig. 9B), and also involved in ECM–receptor interaction, Focal adhesion, Human papillomavirus infection, PI3K-Akt signaling pathway, Toll-like receptor signaling PI3K-Akt signaling pathway, Toll-like receptor signaling pathway (Fig. 9C).