to acid chemical and other biological processes (Fig. 9B, Table 2), meanwhile, collagen IV was mainly enriched in ECM–receptor interaction, Focal adhesion, Human papillomavirus infection, Small cell lung cancer, PI3K-Akt signaling pathway, Amoebiasis, and Protein digestion and absorption (Fig. 9D, Table 3). This evidence concerns the gene AKT1 and human papilloma virus infection.