The genes from our potential hypomethylated biomarkers that have no reported relationship with thyroid cancer include LHX9, MEIS1, GSX2, PITX3, HMX2, PHOX2A, POU6F1, SEBOX, DLX3, TSHZ1, RAX2, ADNP, and HDX. The gene discussed is HDX; the disease is thyroid cancer.