PTPN12 and breast cancer: As for the breast cancer lines, cJun and p27 were recruited to the +2 kb PTPN12 site in a p27-dependent manner, with higher enrichment in UMUC3 overexpressing p27CK-DD than in vector control and loss of cJun binding upon p27 knockdown UMUC3-LuL2 (Fig. S4f, g).