These pathways included ‘IL-17 signaling’, ‘JAK-STAT signaling’, ‘mTOR signaling’, ‘PI3K-Akt signaling’, ‘MAPK signaling’, ‘Ras signaling’, ‘TGFbeta signaling’, ‘breast cancer’ and, most notably, ‘signaling pathways regulating pluripotency of stem cells’ (Fig. 2a). This evidence concerns the gene AKT1 and breast cancer.