PIK3CA and breast carcinoma: These pathways included ‘IL-17 signaling’, ‘JAK-STAT signaling’, ‘mTOR signaling’, ‘PI3K-Akt signaling’, ‘MAPK signaling’, ‘Ras signaling’, ‘TGFbeta signaling’, ‘breast cancer’ and, most notably, ‘signaling pathways regulating pluripotency of stem cells’ (Fig. 2a).