Meanwhile, the results of the KEGG enrichment analysis demonstrated that these ferroptosis-related DEGs were significantly enriched in Ferroptosis, Apoptosis, IL-17 signalling pathway, Autophagy-animal, Toll-like receptor signalling pathway, Necroptosis, NF-kappa B signalling pathway, HIF-1 signalling pathway, Alzheimer’s disease. Here, HIF1A is linked to early-onset autosomal dominant Alzheimer disease.