Preliminary evidence show that a high platelets count is associated with LAV-BPIFB4 genotype with respect to WT and hetero-BPIFB4 patients of a small cohort of COVID-19 individuals in which BPIFB4 has been previously described to have a favorable prognostic relevance [21] (Fig. s3). This evidence concerns the gene BPIFB4 and COVID-19.