With the activation of chemoreceptors, the presence of arousals, and the relief of airway obstructions following, these alternations contribute to tachycardia and sympathetic stimulation, further leading to pseudofluid overload, encouraging the secretion of atrial natriuretic peptide (ANP) and suppressing the secretion of antidiuretic hormone (ADH). The gene discussed is NPPA; the disease is Airway obstruction.