SOD1 and amyotrophic lateral sclerosis: At 10–2, we observed matrix inhibition of ThT fluorescence in several ALS spinal cord homogenates, but at 10–3, 10–4, and 10–5 tissue dilutions, the sALS, SOD1 fALS, and C9ORF72 fALS spinal cords usually gave enhanced ThT fluorescence compared to that elicited by the negative control spinal cords (Figs. 2, 3, 4, 5).