Interestingly, tumor cells from patient A3 had chromosomal losses of chr14q and chr17p compared to immune cells, while tumor cells from patient A4 had chromosomal losses of chr17p, which were consistent with the genomic features of SHH (Figure 2A; Figures S3C,D, and S4, Supporting Information).[7, 26] We also observed distinctive CNV events in tumor cells from different patients, such as chromosomal loss of chr17p in G8 and chromosomal gain of chr3p in both patients G8 and C3 (Figure 2A; Figure S3I,J, Supporting Information). This evidence concerns the gene SHH and neoplasm.