Notably, FABP4 deletion plus TRM cell depletion exhibited a synergistic effect on suppression of T1D progression in mice as indicated by their diabetic incidence, pancreatic injury, expression of CXCL10, and T cell infiltration profile (Figure 5C–I), which highlights the pathogenic effect of both FABP4 and TRM cells. This evidence concerns the gene FABP4 and type 1 diabetes mellitus.