CDX2 and neoplasm: Consistent immunohistochemical profile that was positive for SATB2, INSM1, synaptophysin, keratins (AE1/AE3, CAM5.2) and focal CDX2 with occasional weak GATA3was found in these patients, supporting that middle ear adenoma, middle ear carcinoid, or middle ear neuroendocrine adenoma/tumor are the same tumor (3).