Direct neuroprotective effects (15). Detection of toxic substances in the body and reduction of the risk of diseases caused by them through activation of AhR (13). Activation of AhR exerts an immunosuppressive effect and promote the immune escape of tumor cells (13). Inhibition of osteoblast differentiation and promotion of osteoclast action (83). Enhance the differentiation of Treg cells, modulates immune response (12). Vasodilation (62). This evidence concerns the gene AHR and neoplasm.