The KEGG pathway enrichment analysis revealed the most enriched pathways were TGF-β signaling pathway (path:hsa04350), cellular senescence (path:hsa04218), hippo signaling pathway (path:hsa04390), diabetic cardiomyopathy (path:hsa05415), and relaxin signaling pathway (path:hsa04926) (Figure 2C). The gene discussed is TGFB1; the disease is diabetic cardiomyopathy.