Leukocyte adhesion, which we found is increased between microglia and neutrophils via Bst2 and Icam1 and microglia and monocytes via Icam1, Bst2, and several integrins, but dysregulated in NKs and adaptive immune cells, has not been directly examined in the brain under conditions of peripheral inflammation, but it has been observed in the human lymphatic system[84], in vitro tumor systems[85, 86], and mouse kidney[87] after LPS exposure. This evidence concerns the gene BST2 and neoplasm.