Although expressions of three RPL15 transcripts were detected, they all encoded the same PFKM) affected by SF3B1, SRSF2, and U2AF1 mutations in MDS patients reported previously.65 In our K562-U2AF1S34F model cell line, SF1–8 markedly altered the isoform patterns of PICALM, ERGIC3, RUSC1 discussed previously (Fig.5), BCOR, and MRKN1 (Fig.S4). The gene discussed is PICALM; the disease is myelodysplastic syndrome.