GNRH1 and posterior cortical atrophy: Androgens are critical stimulators of PCa, and in men with locally advanced and metastatic PCa, initial treatment is focused on the suppression of androgens by ADT, generally using gonadotropin-releasing hormone (GnRH) agonists (GnRHa) (also known as luteinizing hormone-releasing hormone [LHRH] agonists) or GnRH antagonists as the first-line option [1, 2].