Due to the high density of GLP-1 receptors and its radiolabeled analogs like exendin 4 receptors on insulinoma, GLP-1 receptor scans like Ga 68 DOTANOC PET-CT, Ga 68 DOTATATE PET-CT, and Ga 68 NOTA-exendin-4 PET-CT are being used for localization of insulinoma with sensitivity upto 98%. This evidence concerns the gene GLP1R and pancreatic insulinoma.