ALMS1 and blindness (disorder): An ALMS1 gene premature termination codon (p.Arg4052Glyfs*2) is produced by a homozygous frameshift deletion in exon 20 (c.12154_12166del), according to whole-exome sequencing of a 10-year-old Saudi girl who presented with diabetic ketoacidosis, hearing loss, and blindness [15].