This supports the idea that early alopecia could be a clinical marker of insulin resistance. In the present study, androgenic alopecia and alopecia were not statistically significant and were more common in participants with normal waist circumference; despite that, it was shown that insulin favors vasocontraction and nutritional deficiency in hair follicles and enhances the effect of dihydrotestosterone (DTH) on follicular miniaturization resulting in alopecia [19]. This evidence concerns the gene INS and alopecia.