MUC1 and apocrine adenocarcinoma: 1,5 Cytokeratin AE1/AE3, CAM5.2, epithelial membrane antigen (EMA), smooth muscle antigen (SMA), periodic acid-Schiff positive with diastase resistance, and GCDFP-15 are all beneficial in confirming the diagnosis.8 Wide local excision is the preferred method of management of primary cutaneous ductal apocrine carcinoma.