Among these antibodies lupus anticoagulant (LAC), anticardiolipin antibodies immunoglobulin M/immunoglobulin G (aCL IgM/IgG), and IgM/IgG anti-β2-glycoprotein I (aβ2GPI IgM/IgG) are crucial for diagnosing APS. The gene discussed is CD40LG; the disease is autoimmune polyendocrinopathy.