MT-RNR2 and early-onset autosomal dominant Alzheimer disease: However, according to bioinformatics gene data from TargetScan, miR-5193 was predicted to target TRIM11 (Pan et al., 2019) and early published studies have identified TRIM11 involvement in neurodegenerative disorders (Lee et al., 2013) as well as in the regulation of Alzheimer’s disease by destabilizing intracellular humanin (Niikura et al., 2003).