Furthermore, a meta-analysis by Liu S [57], confirmed a significant association between the rs2228570 VDR gene variant and GDM in the recessive model in the overall population, further subgroup analysis by race confirmed its significant association in the Caucasian population and suggested that FokI- rs2228570 along with ApaI (rs7975232) VDR gene variant could potentially be used as a molecular biomarker in screening and diagnosing GDM [57]. This evidence concerns the gene VDR and gestational diabetes.