The results of the current study showed that QFM combined with PD-1 inhibitor improved CD8+ T-cell status, increased the proportion of IFN-γ+ cells and the content of IL-2, TNF-α and IFN-γ in the serum samples of LLC-luc tumor-bearing C57BL/6 mice, indicating that QFM combined with PD-1 inhibitor could promote the infiltration of CD8+ T-cells and the release of IFN-γ, thus suppressing the tumor. The gene discussed is CD8A; the disease is neoplasm.