CSF3 and cancer: However, in a meta-analysis that evaluated the safety and efficacy of adding G-CSF to antibiotics when treating chemotherapy-induced FN in patients with cancer, no significant difference was found in the incidence of deep VTE (risk ratio 1.68, 95% CI [0.72–3.93], P = 0.23) in individuals treated with G-CSF plus antibiotics compared with those treated with antibiotics alone.